Through this letter, we learn of the despair of Jim and his children at Kate's death, and of the subsequent meaninglessness of their lives.
"Faced with such horror, we are compelled to turn the despair in our hearts into unshakeable resolve that this will not happen to our children, " she said.
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There are those, like myself, who agree that we do need to do something but despair at anyone ever actually doing the right things.
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Mr Speaker, in the past few days we have seen a range of emotions sweep this country: anger, fear, frustration, despair, sadness - and finally a determined resolve that we will not let a violent few beat us.
We assume that only a person ensnared in deep despair could do such a thing.
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But human beings fall easily into despair, and from the very beginning we invented stories that enabled us to place our lives in a larger setting, that revealed an underlying pattern, and gave us a sense that, against all the depressing and chaotic evidence to the contrary, life had meaning and value.
However, the addiction aside, I can personally acknowledge the destruction and despair that is the cost of every moment we use any piece of technology that is powered by electricity or oil.
To break the old patterns, to break the cycle of insecurity and despair, all of us must say publicly what we would acknowledge in private.
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We wanted to convey a message to poor and illiterate families in despair: searching for family?
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But as hard as it may be, we should not, and cannot, give in to cynicism or despair.
"When we won the Super Bowl, it was like a veil of frustration, despair and negativity was lifted from the eyes of just about every citizen, " Nagin told CNN.
Helping them is our duty, it is absolutely essential that we improve their outcomes, but tearing down the whole system out of our despair at their plight will not help them.
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Down through the years I have seen despair and frustration evolve into optimism and progress and, even now, we must not abandon efforts to achieve permanent peace for Israelis and freedom and justice for Palestinians.
Although we like to think otherwise, society is still hideously homophobic and image conscious and I despair for Will because of this.
Consider that we already grasp, no matter how much we wish to deny it, that even a victory under those conditions traces back to despair, if despair is our point of departure.
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We have an historic opportunity in the world to extend prosperity to regions that have only known poverty and despair.
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