摘要: 目的评价携带人uPA基因的腺病毒(AduPA)转染骨髓源性肝干细胞(BDLSC)的效率,在BDLSC中的表达及其对BDLSC增殖和分化的影响.方法利用淤胆型肝损.
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骨髓源性肝干细胞（bone marrow-derived hepatocytestem cells,BDHSC）因其取材方便，自体来源无免疫排斥，能在体外扩增并进行基因修饰，在肝细胞移 植领域显示了广阔的应用前景...
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应用骨髓源性肝干细胞 BMDLSC ; bone marrow derived liver stem cell
目的寻找骨髓源性肝干细胞的表面标记，进行定向分化及脾内移植研究。
Objective To identify the surface marker of bone marrow-derived liver stem cells, isolate the stem cells, and investigate the differentiation and intrasplenical transplantation of the stem cells.
目的探讨骨髓源性肝干细胞（BMDLSC）移植对肝纤维化病变的影响。
Objective To explore the action of transplantation of bone marrow-derived liver stem cells(BMDLSC)on hepatic fibrosis induced by alcohol in mice.
文章就骨髓源性肝干细胞的分离、培养、纯化、诱导分化、检测及肝内移植的可能机制和应用前景进行综述。
The article covers isolation, culture, differentiation, tests, possible mechanisms of engraftment in the liver and application prospect of bone marrow-derived liver stem cells.
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