与骨髓造血微环境 hemopoietic inductive microenviromentHIM
骨髓造血微环境 hematopoietic inductive microenvironment ; HM ; HIM
健康的骨髓造血微环境 HME
BACKGROUND &OBJECTIVE: More and more studies indicated that microenvironment plays a major role in growth, survival, and drug resistance of myeloma cells. Thalidomide is one of agents targeting the bone marrow microenvironment.
背景与目的:越来越多的研究表明,骨髓瘤细胞的生长、生存以及耐药的产生与骨髓微环境密切相关。
参考来源 - 沙利度胺对难治、复发多发性骨髓瘤患者骨髓微环境的影响·2,447,543篇论文数据，部分数据来源于NoteExpress
骨髓间充质干细胞的增殖、分化及迁移等生物学特性受骨髓微环境的调节。
Hematopoietic inductive microenvironment (HIM) is the site of implantation, proliferation, differentiation, and development for hematopoietic stem cells (HSC).
结论来源于胎儿骨髓的亚全能干细胞可以在体外及肝脏微环境下转化为肝细胞样细胞。
Conclusion The human fetal bone marrow postembryonic pluripotent stem cells can differentiate to hepatocyte - like cells in vitro or in hepatic microcirculation.
目的：进一步探讨外周血干细胞移植后患者骨髓造血微环境损伤的机理。
Objective: to investigate the injury mechanism of bone marrow hematopoietic microenvironment from PBSCT patients anterior and post pretreatment.
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