推荐的首剂量是5克时，发现药物耐受性普遍良好，副作用从轻度到中度不等。

At the proposed starting dose of 5 grams, the drug was found to be generally well tolerated with side effects that were mild to moderate.

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该药在1999年首次被作为处方药批准使用，而今后需大剂量将该药用于肥胖的药物治疗时仍需持有医师的处方。

The drug, which was originally approved for prescription in 1999, will retain prescription status at higher doses for the medical treatment of obesity.

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结论小儿原发性肾病综合征首用常规激素诱导治疗8周，不缓解者可考虑用大剂量地塞米松冲击治疗。

Conclusion Children's primary nephrotic syndrome should be treated for 8 weeks by routine hormone induction therapy, if no remission, impulsion therapy could be used.

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