这些剂量分别是20倍和6倍于最大临床预期剂量。(60千克的人，剂量30毫克)。

These dosages were 20 and 6 times the maximum anticipated clinical dosage (30 mg dosage, 60 kg human), respectively.

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患者还可能对某种药物产生耐受性，这意味着患者必须服用比以往更大的剂量才能产生预期的效果。

A patient may also acquire a tolerance for a certain drug, which means the patient has to take ever larger doses to produce the desired effect.

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然后，在没有改变剂量的情况下，病人被告知已停止施用止痛剂而预期疼痛，指数随即上升至64。

Then, without changing the dose, the patients were then told the painkiller had been withdrawn and to expect pain, and the score went up to 64.

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