顺铂 DDP ; cis-platinum ; PDD
顺氯氨铂 DDP ; CDDP ; cisplatin ; cis-platinum
注射用顺铂 Cisplatin for Injection ; Cisplatin for Inj
大剂量顺铂 HD-DDP ; HD-PDD ; high-dose cisplatin
顺糖氨铂 Nedaplatin ; diammineplatinum
顺铂耐药 Cisplatin resistance ; drug resistance to cisplatin ; cisplatin-resistant
注射用顺氯氨铂 cisplatin vial
顺铂注射液 Cisplatin lnjection ; Cis-platinInjection
小剂量顺铂 LD-DDP ; DDP
顺铂氯化钠注射液 Cisplatin and Sodium Chloride Injection
顺铂通常第一次给药时有效，它有一个主要的缺陷：肿瘤获得耐药性，而且重新开始生长。
While cisplatin is often effective when first given, it has a major drawback: Tumors can become resistant to the drug and start growing again.
现在，MIT癌症生物学家已经展现了耐药性是如何增加的，这项发现可能帮助研究员设计可以克服顺铂耐药性的新药。
Now, MIT cancer biologists have shown how that resistance arises, a finding that could help researchers design new drugs that overcome cisplatin resistance.
当PIDD水平在肺癌细胞人为增加时，它们对顺铂耐药性增强。
When PIDD levels are artificially increased in human lung cancer cells, they become more resistant to cisplatin.
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