Most of anticancer agent targets in biology body are DNA molecules,which have three action styles:(1) Drugs and DNA formed non-covalent compounds,and combine with DNA through hydrogen bond.
绝大多数抗癌剂在生物体内的靶点是DNA分子,其作用方式大致分为三种:(1)药物与模板DNA形成非共价复合物,主要与DNA以氢键相结合。
参考来源 - 生物小分子与DNA相互作用的光谱及二维核磁的研究·2,447,543篇论文数据,部分数据来源于NoteExpress
扼要概述了非共价法制备分子模板聚合物的影响因素及控制措施。
Influence factor and control measure on the preparation of molecular template polymer by non-covalence method were reviewed concisely.
基于非共价相互作用的分子识别和自组装是超分子化学研究的两个重要的领域。
Molecular recognition and molecular self-assembly through the non-covalent bond is the two important parts of supramolecular chemistry.
该分子能够共价或者非共价连接到选自 如下的成员:胞外基质组分,生长因子及其组合。
This molecule is capable of either covalently or non-covalently attaching to a member selected from an extracellular matrix component, a growth factor, and combinations thereof.
There's not actually chemical covalent bonds that are formed but it's a non-covalent interaction, usually dominated by hydrogen bonding.
所以配体和受体之间不生成共价键,这是一种非共价化合反应,它们通常以氢键相联
But the beauty in this calculation is it shows that this concept of electron sharing in an unequal manner is sound and it gets you into the right ballpark.
但在这个计算过程中,真正漂亮的是对电子,非平均共价的考虑很完全,从而指引我们向一个正确的方向思考。
Now, usually this is a non-covalent interaction.
这通常是一种非共价化合反应
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