雷莫司琼是一种白色结晶药物,是用于治疗恶心和呕吐的5-羟色胺5-HT 3受体拮抗剂。拉莫司琼还指示用于治疗“腹泻型肠易激综合征的男性”。在印度,它以“IBset”的品牌名称销售。它仅授权在日本和选定的东南亚国家使用。在日本,其以商品名Iribo(イリボー)出售。在其它地方,它通常以商品名Nasea出售,在印度以Nozia(300mcg / ml Inj。&100mcg Tab。)出售。
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目的探讨盐酸雷莫司琼注射液安全性,为临床用药提供参考。
Objective It's to provide reference for clinical utilization that the safety of ramosetron hydrochloride injection was studied.
目的观察雷莫司琼预防术后患者自控静脉镇痛(PCIA)期间恶心呕吐的防治效果及安全性。
Objective To observe the efficacy and safety of ramosetron for preventing nausea and vomiting during postoperative patient controlled intravenous analgesia(PCIA).
结果盐酸雷莫司琼注射液对豚鼠无致敏作用,对家兔红细胞无明显体外溶血及致凝集作用,对家兔血管无明显刺激作用。
Results Ramosetron hydrochloride injection has no hypersensitivity to guinea pig, no hemolysis and agglomeration to red blood cells of rabbit, no obvious stimulation to blood vessels of rabbit.
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