紫杉烷类药物具有良好的抗肿瘤活性，然而其极差的水溶性却限制了临床应用。
Taxanes have good antineoplastic activity, but the clinical application has been limited owing to the poor water solubility.
由于M受体拮抗剂缺乏对受体的选择性和对组织的特异性，限制了其临床应用。
However, the lack of receptor subtype selectivity or organ specificity of m receptor antagonists limited their clinical application.
造血干细胞数量限制了其临床应用。
The number of haemopoietic stem cells(HSCs) limited their clinical application.
应用推荐