目的研究多发性骨髓瘤(MM)患者13号染色体长臂特定位点的缺失及与临床表现、预后的关系。
ObjectiveTo explore the specific locus deletion of the long arm of chromosome 13 and its relationship with the clinical behavior and prognosis of multiple myeloma (MM).
结论:本文的研究结果提示X染色体长臂末端可能是卵巢早衰的特异性基因区段并与X染色体末端端粒的缺失有关。
Conclusion: The result showed that terminal deletion of Xq and telomeric deletion of X chromosome were important factors of premature ovarian failure.
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