神经元在受电刺激时诱发AP(action potential),依次由局部电位、锋电位和后电位三部分组成。锋电位是AP的特征部分,通常说的AP主要指这一部分。锋电位包括从局部电位基础上迅速去极化的上升分支,即去极化相,并超过零电位而发生膜电位的翻转,即反极化相或超射,随后膜电位迅速复极化形成下降分支,即复极化相。 锋电位(spike potential)在刺激后几乎立即出现,潜伏期不超过0.06毫秒。其幅度为静息电位与超射值之和,并服从全或无定律和非递减性传导。
The spontaneous activity is composed by multiple signals with different frequency, and the spikes firing are high-frequency signals.
自发电信号是由多个频段组成,锋电位发放是高频信号。
参考来源 - 培养神经元网络自发电信号的特性分析The accuracy of the virtual instrument was confirmed by compared with commercial spike sorting software.
最后,将锋电位分类虚拟仪器和同类型的商用软件进行比较,通过大量记录数据的分类分析结果对比,验证了该虚拟仪器聚类分析的准确性。
参考来源 - 基于LabVIEW的神经信号记录及分类的虚拟仪器·2,447,543篇论文数据,部分数据来源于NoteExpress
最后用训练好的神经网络锋电位信号进行分类。
The manual network was trained and then identifies the spikes to different classifications.
在受到长的强度不变的去极化电流时,多数神经元表现出明显的锋电位频率适应。
When presented with long depolarizing current pulse of constant amplitude, most of the neurons exhibited pronounced adaptation of spike frequency.
爆发活动信号高能量所在频段比随机单发锋电位活动和连续发放锋电位活动信号的要低。
The frequency bands of high-energy for burst activities are lower than those of random single spike firing and continuous single spike firing.
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