钙通道 是一类跨膜糖蛋白，广泛存在于机体各种类型的组织细胞中。调控钙离子的运输。
钙通道阻滞药 Calcium channel blocker ; CCB ; CBDs
电压依赖性钙通道 voltage-dependent calcium channel ; Voltage-gated calcium channels ; voltage dependent channel ; VDCCS
钙通道阻滞剂中毒 Poisoning by calcium-channel blockers
电压门控钙通道 VGCC ; voltage-gated calcium channel
钙通道阻滞剂 CCB
钙通道抑制剂 calcium channel blockers ; Calcium-passage inhibitor
性钙通道 SoCC ; receptor-operated calcium channel ; voltage-gated calcium channels ; ROCCs
钙通道拮抗剂 CCB ; calcium channel antagonists
型钙通道 LCCs ; neuronal calcium channel ; L-type calcium channels ; L-type voltage dependent calcium channel
电压门控性钙通道 voltage-gated calcium channel ; VGCC
The calcium channel block and neuroprotective effect of agmatine and 13 analogues were evaluated.
对13个化合物的钙通道阻断作用和神经元保护作用进行了初步评价。
参考来源 - 胍丁胺衍生物的设计合成及生物活性研究The decreasing effect of anandamide on Ca2+i may be related with inhibition of Ca2+ influx from L-type Ca2+ channel and releasing of Ca2+ from sarcoplasmic reticulum.
Anandamide降低心室肌细胞内游离钙效应与其抑制心室肌细胞L型钙通道和肌浆网内钙释放有关。
参考来源 - 内源性大麻素物质anandamide对大鼠的心脏保护作用及其机制Conclusion Ketamine can inhibit I_(Ca-L) of guinea pig ventricular myocytes in a concentration-dependent manner, which might explain its negative inotropic effect. Ketamine inhibits L-type Ca~(2+) channel in its inactivation status.
结论：氯胺酮可浓度依赖性地阻滞豚鼠心室肌细胞L型钙电流，主要作用于钙通道的失活态，为氯胺酮抑制豚鼠心室肌收缩力的机理之一。
参考来源 - 氯胺酮对豚鼠、大鼠心室肌细胞膜离子通道的影响EGTA and BAPTA, two Ca2+ chelators, but not nifedipine, an L-type Ca2+ channel blocker, prevented GRIP1 degradation.
两种钙离子的螯合剂EGTA和BAPTA都可以阻断GRIP1的降解,而L型钙通道的阻断剂nifedipine却没有作用。
参考来源 - 1.谷氨酸刺激引起泛素蛋白酶系统降解GRIP1可以影响AMPA受体在细胞膜的分布 2.泛素蛋白酶系统调节Akt分布影响海马神经元极性These results suggest that proton pump is a positive regulator which accommodates stomatal movement by enhancing Ca~(2+) influx through a voltage-dependent, hyperpolarization-activated, inward-recitified Ca~(2+)-permeable channel in plasma membrane of Vicia faba guard cell.
实验结果初步证明,保卫细胞质膜质子泵在气孔运动过程中发挥重要的正向调控作用,这一作用有可能是通过激活质膜上超极化激活钙通道促进细胞内钙离子浓度升高实现的。
参考来源 - 质膜质子泵对蚕豆保卫细胞质膜钙通道活性的影响·2,447,543篇论文数据，部分数据来源于NoteExpress
钙通道阻滞剂降低后负荷，而对前负荷几乎没有作用。
Calcium channel blockers reduce afterload with little effect on preload.
药物治疗组有稍微更多的倾向服用钙通道阻滞剂和止痛的硝酸酯类药物。
The drug therapy group was slightly more likely to have taken calcium-channel blockers and pain-killing nitrates.
另外，有些药物可以直接缓解血管压力，如钙通道阻滞药物，和其它血管放松药物。
Drugs that directly relax the blood vessels. These include calcium channel blockers (CCBs) and other direct dilators (relaxers) of blood vessels.
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