钙粘素（cadherin）属亲同性CAM，其作用依赖于Ca2+。至今已鉴定出30种以上钙粘素，分布于不同的组织。 钙粘素分子结构同源性很高，其胞外部分形成5个结构域，其中4个同源，均含Ca2+结合部位。
E 钙粘素表达与肿瘤细胞分化呈正相关；
The expression of E-cadherin was associated with differentiation.
钙粘素异常表达在门静脉有无癌栓中呈明显相关（P<0.01）。
The abnormal expression of E-cadherin significantly was related with portal vein embolus or not(P< 0.01).
结论甲状腺癌组织vegf、MMP - 9及e钙粘素的表达与甲状腺癌的侵袭及转移有关，可作为甲状腺癌患者的预后指标。
Conclusion The expression of VEGF, MMP-9, E-cadherin is associated with invasion and metastasis of thyroid carcinoma, which may serve as prognosis indexes of thyroid carcinoma.
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