重链大小约为轻链的2倍,含450~550个氨基酸残基,分子量约为55或75kD。每条H链含有4~5个链内二硫键所组成的环肽。
Sequence analysis ofpositive clone 20 showed that the light chain variable domain (VK) gene belong toVK9 subgroup,the heavy chain variable domain(VH) gene belong to VH7 subgroup,most high identity is respectively 94.87% and 97.85%.
对单抗克隆20进行测序,结果表明轻链V区基因属VK9亚群,重链V区基因属VH7亚群,经NCBI BLAST和IMGT分析均为鼠源性抗体基因,最高同源性分别为94.87%和97.85%。
参考来源 - 副粘病毒Tianjin株在婴幼儿下呼吸道感染情况调查及噬菌体抗体文库的构建筛选Then were immunostained to determine the presence of fast,slow and neonatal myosin heavy-chain isoforms.
免疫组化染色切片确定眼轮匝肌中肌球蛋白重链单体各亚型(快型、慢型、新生儿型)的存在。
参考来源 - 甲状腺功能亢进对家兔眼轮匝肌的影响Myosin heavy chain (MHC) degraded markedly when silver carp myofibril was incubated at 55~60℃ as shown by SDS-PAGE.
SDS-PAGE结果显示肌原纤维在55~60℃下加热后肌球蛋白重链有明显的分解现象。
参考来源 - 鲢鱼肌原纤维结合型丝氨酸蛋白酶的研究·2,447,543篇论文数据,部分数据来源于NoteExpress
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