有机相中应用酯化反应，酶法催化拆分消旋醇是获得光学活性醇的重要途径。
The main route for obtaining optically active alcohols is resolution of racemic alcohols catalyzed by enzyme in organic solvents by the esterification reaction.
研究人员采用多种方法合成单一构型的地尔硫卓手性中间体，其中包括化学拆分、化学不对称合成以及化学-酶法合成等方法。
Many methods were investigated for the synthesis of the single enantiomer of the chiral intermediate, including chemical resolution, chemical asymmetric synthesis and chemo-enzymatic synthesis.
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