※ N端乙酰化( Acetylation ),C端酰胺化( Amidation ) :N端乙酰化和/或C端酰胺化作用可以减少多肽的整体电荷,但溶解度可能会下降。
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5-氨基-2-(4-氨基苯)苯并恶唑合成研究 关键词: 聚合物;苯并恶唑;酰胺化;催化加氢[gap=747]Key words: polymer;benzoxazole;amidation reaction;catalytic hydrogenation
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Levetiracetam was prepared from L-methionine via reduction-dethiomethylation, esterification, ammonolysis, amidation and intramolecular cyclocondensation reaction with 44.6% overall yield.
以蛋氨酸为原料经还原脱硫甲基化、酯化、氨解、酰胺化及分子内缩和成环4步反应合成得到了左乙拉西坦,总收率44.6%。
参考来源 - 抗癫痫治疗药物左乙拉西坦的合成研究The second one is about the direct oxidative formation of amides from aldehydes and amines using a hypervalent iodine(III) reagent or an ion-supported hypervalent iodine(III) reagent.
第二章,介绍了用二乙酸碘苯和离子支载二乙酸碘苯进行醛和胺直接氧化酰胺化的研究。
参考来源 - 醛和胺直接氧化酰胺化和苄卤的氧化研究To avoid the hydrolyzation of the expressed product by the cellular proteases and get more stable humanα-defensin it was attempted to express humanα-defensingenes in cyclic or amidation form.
为了避免表达产物水解,得到更稳定的人α-防御素,以环化形式和酰胺化形式表达人α-防御素基因。
参考来源 - 人α·2,447,543篇论文数据,部分数据来源于NoteExpress
通过正交实验对菜籽油与单乙醇胺的酰胺化反应进行了研究。
The amidation reaction between rapeseed oil and monoethanolamine was studied via orthogonal experiment.
方法以对羟基苯甲酸为原料,经三步合成,即原料的醚化、酰氯制备和酰胺化。
Methods The substance was synthesized from P-hydroxybenzoic acid through three steps, those are etherification, preparation of acyl halide and amidation of the raw material.
研究了环酐与苯胺和苯酚的酰胺化及酯化反应,优化了酰胺化及酯化反应条件。
The amidation and esterification of different cyclic anhydrides with aniline and phenol gave different major products, and the routes were optimized.
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