复方鳖甲软肝片抑制大鼠酒精性肝纤维化作用机制研究 关键词】 复方鳖甲软肝片；酒精性肝纤维化；转化生长因子-β1；大鼠 [gap=1044]Key words：Compound Biejiaruangan Troche；alcohol hepatic fibrosis；TGF-β1；rat
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酒精性肝纤维化（alcoholic liver fibrosis，ALF）是长期大量饮酒 所致的一种肝脏疾病，是各种慢性酒精性肝病（Alcoholicliverdisease...
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酒精性肝病发病机制研究进展 r dieease，ALD）包括酒精性脂肪肝（alcoholic fatty liver,AFL）、酒精性肝纤维化（alcoholic fibrosis，AF）、酒精性肝炎（alcoholic hepatitis，AH）和酒精性肝硬化（alcoholic ci
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酒精性肝纤维化和肝硬化 Alcoholic fibrosis and sclerosis of liver
Objective To induct a relatively simple and feasible rat model for further pathogenesis of alcoholic liver fibrosis.
目的 :探索简便、经济的大鼠酒精性肝纤维化造模方法。
参考来源 - 大鼠酒精性肝纤维化模型的构建Conclusions It was suggested that chondroitin sulfate might have therapeutic effects on liver fibrosis induced by alcohol in mice, by inhibiting the MDA、NO、NOS、TGF-β1、PDGF and TIMP-1 levels.
结论硫酸软骨素对酒精性肝纤维化有治疗作用,其作用机制可能与影响MDA、NO、NOS、TGF-β1、PDGF和TIMP-1的表达水平相关。
参考来源 - 硫酸软骨素对大鼠酒精性肝纤维化模型的影响·2,447,543篇论文数据，部分数据来源于NoteExpress
结论复方鳖甲软肝片能够有效阻止和逆转酒精性肝纤维化的进程。
Conclusion Compound Biejiarangan Troche has effect of inhibiting and reversing alcohol hepatic fibrosis in rats.
通过递增乙醇浓度，日3次胃内灌注乙醇来复制酒精性肝纤维化动物模型。
The rat model of alcoholic liver fibrosis was induced by intragastric infusion of increasing concentration of ethanol 3 times per day.
目的探讨复方鳖甲软肝片对实验性大鼠酒精性肝纤维化的抑制作用及机制。
Objective to probe into the inhibiting action of Compound Biejiarangan Troche on alcohol hepatic fibrosis in rats.
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