复方丹参速释微丸 compound Danshen immediate-release pellets
Methods:Immediate release pellets were manufactured by extrusion/spheronization technology. The operation of bottom-spraying in the fluid-bed equipment was conducted to enteric-coating using Eudragit L-30D-55 and sustained-release coating using Surelease.
方法:采用挤出滚圆法制备速释丸,流化床底喷包衣制备肠溶和缓释微丸。
参考来源 - 盐酸青藤碱缓释组合微丸系统的研究·2,447,543篇论文数据，部分数据来源于NoteExpress
目的制备复方丹参速释微丸，使理化性质差异较大的各成分达到同步释放。
Objective To prepare compound Danshen immediate-release pellets and obtain the synchronous release rate of components with significant difference of physicochemical properties.
目的应用挤出滚圆法制备复方醋氯芬酸速释微丸，研究制备的处方和工艺。
Objective To prepare compound aceclofenac pellets by extrusion-spheronization and study the influence of formulation and process parameters on the properties of the pellets.
结论成功地制备了复方醋氯芬酸速释微丸，该制备工艺重现性好、质量高、具有理想的速释效果。
Conclusion The compound aceclofenac pellets were successfully prepared by extrusion-spheronization with good reproducibility and high-quality.
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