而辛伐他汀组与相同时点高脂饮食组比较，上述指标均明显减轻。

However, all of these ameliorated in simvastatin group, compared to high fat diet group at each time point.

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高脂组、吗多明和辛伐他汀干预组尿蛋白在6周起才出现明显增加（P<0.01），且辛伐他汀组又显著低于高脂组（P<0.01）；

The urinary protein excretion was increased significantly after 6 weeks (P<0.01), and the level was significantly lower in treated groups (P<0.01).

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与安慰剂组比较，辛伐他汀组内膜增生减少，而管腔面积的减少减轻，与之相对应的是PAPP - A的表达及血管组织CD 40l蛋白含量也明显降低。

Compared to placebo group, simvastatin can inhibit the vascular intima proliferation the expression of PAPP-A and CD40L were also decreased significantly.

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