...gcell）中呈组成性激活 （constitutive active），是多种信号途径如Wnt／p．连环素、AP-1等的负调节因子 （negative regulator）嗍，也可被其它激酶如PKB、PKC和P13K等磷酸化 （Ser21．GSK3e．Ser9．GSlOIB），引起活性抑制【7，9’101． West掣¨1发现尼古丁...
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细胞因子信号转导抑制因子3 (SOCS - 3)是白细胞介素6 (IL - 6)信号转导的负调节因子。
Suppressor of cytokine signaling (SOCS) -3 is a negative regulator of interleukin (IL) -6 signal transduction.
最初发现SOCS2是GH信号的负性调节因子，后来发现胰岛素与SOCS2也有密切关系。
SOCS2 was primarily known as a negative regulator of GH signaling which was found closely associated with insulin later.
结果多种致热性细胞因子和负调节介质共同作用，使机体温核集团对致热原作用发生指向性调控。
Pyrexia is an effect due to pyretic cytokine and negatively regulating factors, the reaction is about the regulatory increasing of temperature caused by the response of pyrogen from the body.
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