如果我是酵,我会成为解螺旋酶,那么我可以解开你的基因。
If I was an enzyme, I'd be helicase so I could unzip your genes.
促进DNA从紧密螺旋的状态到松弛-解螺旋的药物能增加小鼠的记忆力——但是也会产生不必要的副作用。
Drugs that promote this relaxation–unwinding DNA from its tightly coiled configuration–give enzymes access to genes that must be turned on to enable learning.
乙酰化反应使组蛋白让DNA解螺旋,允许了基因的表达发生,因此抑制乙酰化反应将从总体上降低基因的表达。
Acetylation causes histones to unspool their DNA, thereby allowing gene expression to proceed—so decreased acetylation generally reduces gene expression.
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