本品是一种特定的长效血管紧张素转换酶抑制剂。能抑制肾素-血管紧张素-醛固酮系统，从而抑制血管紧张素Ⅰ转换为具有强烈收缩血管功效的血管紧张素Ⅱ。使外周血管阻力降低，血压下降。用于治疗各种程度的原发性高血压和肾性高血压。也可与洋地黄或利尿药合用治疗慢性心力衰竭。
西拉普利（Cilazapril）：起始量lmg，每日1次，渐增至极量5mg，每日1次。培哚普利（PerindO-pril）：起始量2mg，每日1次，维持量2～4mg，每日1次；极量8...
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Objective To study efficacy and safety of cilazapril in treating patients with essential hypertension.
目的 探讨西拉普利治疗高血压的临床疗效和安全性。
参考来源 - 西拉普利和依那普利治疗原发性高血压的临床对照研究 Comparison of Cilazapril or Enalapril in Treatment of Patients with Essential Hypertension·2,447,543篇论文数据，部分数据来源于NoteExpress
结论西拉普利是一种安全和有效的治疗轻中度原发性高血压的药物。
Conclusion Cilazapril is a safety and effective antihypertensive drug in patients with essential hypertension.
目的：为探索西拉普利治疗高血压病疗效及其对胰岛素抗药性的影响。
AIM: To study the effect of cilazapril on insulin resistance (IR) in patients with essential hypertension.
结果两组降压显效率及有效率无显著性差异，但西拉普利治疗组血压波动较小。
Results There were no difference between the two groups on blood pressure effectiveness, but blood pressure was more stable in the cilazapril gro up.
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