目的探讨氧合血红蛋白对体外培养的大鼠脑微血管内皮细胞增殖和凋亡的影响。

Objective to investigate the effect of oxyhaemoglobin on proliferation and apoptosis of cultured rat brain microvascular endothelial cells.

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应用免疫组化方法检测治疗后各组肿瘤组织中环氧合酶-2（COX-2）和血管内皮生长因子（VEGF）的蛋白表达；

Then the volume and weight of tumor, the post-therapeutic weight of mice were studied after 28 consecutive days. The COX-2 and VEGF expression of tumors were detected by immunohistochemistry.

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