在这个无血清培养基中,SSV - NIH3T3细胞可以很好地生长,并具有分泌血小板生长因子样生物学活性物质和致裸鼠肿瘤的能力。
In this SFM SSV-NIH3T3 cells grow well, they keep the ability of secreting platelet-derived growth factor-like material into culture medium and causing tumor growth in nude mice.
目的探讨胶质瘤细胞血小板源生长因子B链的纯合二聚体(PDGFBB)自分泌环活性与其细胞增殖和凋亡的关系。
Objective to investigate the relationship between activity of autocrine loop of platelet derived growth factor BB (PDGFBB), cell proliferation and apoptosis in gliomas.
这一作用可能在血小板活化时细胞骨架重组、形态改变和分泌内含物等一系列变化中起重要作用。
This may be effective in reassembly of the cytoskeleton, change of platelet shape and secretion during activation of the platelet.
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