SITR 1是一种组蛋白脱乙酰基酶，一种能够阻断来自调节基因的转录因子的蛋白质。
SITR1 is a histone deacetylase, a protein that blocks transcription factors from regulating genes.
具体地，本发明显 示E2-EPF5活性的抑制降低VEGF以及其他在低氧应答中由转录因子 HIF-1调节的蛋白质的产生。
In particular, inhibition of E2-EPF5 activity is shown to reduce the production VEGF, as well as other proteins regulated the transcription factor HIF-1, in response to hypoxia.
新近研究提示，在基础和应激条件下，生长激素胰岛素样生长因子胰岛素样生长因子结合蛋白(GH IGF IGFBP)轴对调节肌肉蛋白质代谢起着核心作用。
Recent researches indicate that the GH IGF IGFBP axis plays a crucial part in regulating the metabolism of muscle protein on both basal and stress condition.
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