利用展示有LKVIRK表位的杂合噬菌体作为抗原,免疫C57BL/6J小鼠,然后在小鼠的系统性念珠菌感染模型中评价其免疫保护作用。
The efficacy of hybrid phage particles displaying LKVIRK in inducing immune protection response were studies in C57BL/6J murine model of systemic C.
目的构建表达P30蛋白抗原表位的重组质粒及工程菌,获得纯化的P30蛋白抗原表位,用于检测弓形虫特异性抗体。
Objective To construct a recombinant plasmid containing P30 gene of Toxoplasma gondii and obtain recombinant protein Methods P30 gene fragment was amplified from genomic DNA of T.
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