莱姆症为由Borrelia burgdorferi菌所引发之感染性疾病。这些细菌是经由一种学名为Ixodes scapularis的扁虱的叮咬而传染。由于扁虱非常的小，且被它咬到通常没有感觉，故某人出现莱姆症症状时，通常不记得曾被扁虱咬过；莱姆症最常发生于美国东北及中西部，在美国每个州都曾报告过有此病症出现。
杰克：莱姆症。如果你接触了一些鹿粪，没洗手就吃了三明治，你就会得上莱姆症。
Jack MacReady: lyme disease. You touch some deer feces, and then you... eat a sandwich without washin 'your hands. You got your lyme disease!
首先是在1975让自己看起来是一组青少年关节炎的病例，莱姆症就这样持续的愚弄着病患和医生。
First presenting itself as a mysterious cluster of juvenile-arthritis cases in 1975, Lyme disease continues to fool patients and physicians alike.
虽然对于莱姆病的诊断和治疗有一个大体指南，但是对神经型疏螺旋体症的治疗仍有很大的不确定性，而且，至今仍然没有清楚明确的指南。
Although guidelines exist in the diagnosis and treatment of Lyme disease in general, there is great variability in how neuroborreliosis is treated and little clear guidance is currently available.
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