药物是肝损害的重要病因之一。药物引起肝病的机制因药而异，非常复杂，大多数情况下尚不清楚。有些药物具有直接的毒性作用，由其引起的肝脏损害一般可以预见，而且损害与药物剂量有关，且为某些药物所特有；另一些药物仅偶尔在敏感的个体引起肝损伤，而且与剂量无关，发生与否也难以预测。这种在敏感个体发生的反应常被称为过敏反应，但作为一种真正的变态反应，证据并不充分，所以最好称为特异体质反应。药物的直接毒性和特异体质反应之间的区别并不如以前想象的那样清楚。
药物性肝损害 DILI ; drug-induced liver injury ; medicamentous liver injury ; Drug-induced liver disease
药物性肝病损害 drug inuced liver injury ; DILI
药物相关性肝损害 Drug-related hepatotoxicity ; DRH
又称药物相关性肝损害 Drug-related hepatotoxicity
·2,447,543篇论文数据，部分数据来源于NoteExpress
因怀疑与32例肝损害病例有关，英国一种非处方减肥药正遭到美国食品药物管理局的调查。
A slimming drug available over the counter in the UK is being investigated for links to 32 cases of liver damage by the US Food and drug Administration.
高压的生活再加上对吗啡等止痛药物的依赖，导致她患上了出血性胃溃疡和肝损害。
High living, including a dependence on painkillers like morphine, helped bring her a bleeding ulcer and liver damage; more than once she collapsed dramatically onstage.
在考虑其可能存在某些毒副作用，美国食品药物管理局年初开始对在柜台里名为Alli，主要成份是奥利司他的减肥药进行调查，看它是否与那些肝损害案例有关。
The FDA began investigating orlistat, sold over the counter as Alli, and its potential links to liver damage earlier this year after concerns were raised about potentially harmful side effects.
应用推荐