目的建立以硝苯地平为探针药物测定大鼠和犬肝微粒体活性的HPLC/MS。

OBJECTIVE To establish a HPLC/MS method to determine microsomes activity in vitro using nifedipine as a probe drug.

youdao

结论这种样品处理方法既消除了杂质对药物测定的干扰，也保证了较高的提取回收率。

CONCLUSION the sample pretreatment method established in this experiment is not only of the minimized impurity interference for drug determination, but also of higher drug recovery.

youdao

因此科学家需要去测定低剂量药物是否有减缓人衰老的效果，在没有对免疫系统造成损害的情况下，Kaeberlein说到。

So scientists will need to determine whether lower doses of the drug can offer humans anti-ageing effects without compromising their immune systems, Kaeberlein says.

youdao