生命科学 关键词：诱导性多能干细胞；免疫原性；基因组变异；表观遗传变异；致瘤性 [gap=1181] pluripotent stem cells; immunogenicity; genome variation; epigenetic variation; tumorigenicity
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Results: 1. HL-60 model with high tumorigenicity in nude mice have been Successfully established.
结果:1.成功建立了裸鼠致瘤性逐渐增高的HL-60细胞系。
参考来源 - 裸鼠体内高致瘤HLObjective:To observe the inhibitory effect of AdCMVGM CSF on tumorigenesis and growth of B16 melanoma.
目的 :观察携带鼠粒细胞巨噬细胞集落刺激因子基因腺病毒载体 ( Ad CMVGM- CSF)对B1 6黑色素瘤的致瘤性及抑制作用。
参考来源 - 携带鼠粒细胞巨噬细胞集落刺激因子基因腺病毒载体对B16黑色素瘤的抑制作用·2,447,543篇论文数据，部分数据来源于NoteExpress
目的探讨微囊化技术对细胞异种移植致瘤性的影响。
Objective To study oncogenicity in several microencapsulated cells 'xenograft.
结果大蒜油对癌细胞形态、增殖和致瘤性有明显影响。
Results Cell growth in vitro and tumorigenicity in nude mice were inhibited dramatically by garlic oil.
这可能也是IL—2基因修饰后其致瘤性下降的重要机制之一。
It may be one of mechanisms of decreased tumorigenicity of IL - 2 gene modified tumor cells.
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