目的：建立大黄致泻效价测定的模型和方法，为探索建立基于生物效价检测的大黄品质评价方法提供技术支持。
Objective: to establish a method suitable to determine the purgative biopotency of rhubarb and construct a new quality evaluation pattern of rhubarb.
结论产H2S致泻大肠埃希菌与大肠埃希菌有密切的亲缘关系，是变异的致泻大肠埃希菌，在致泻大肠埃菌中占有较高的比例。
Conclusions Diarrheagenic E. coli of producing H2S has close consanguinity with diarrheagenic E. coli, and they are variant diarrheagenic E. coli, accounting for relative high proportion.
方法 ：采用幽门结扎 ，胃排空 ，胃肠推进运动 ，醋酸扭体反应以及番泻叶致泻模型观察戊己胶囊对胃肠系统的影响。
Method:To use pyloric ligation, gastric emptying, gastrointestinal propulsion, cassia acutifolia Del. inducing purging models to observe the gastrointestinal tract effect produced with Wuji capsule.
应用推荐