目的研究金匮实脾法对实验性肝纤维化大鼠胶原纤维合成与降解的影响。
Objective To explore the influence of spleen-firming therapeutics on synthesis and degradation of collagen fibers of experimental hepatic fibrosis rat.
结果新生儿先天性梅毒可侵犯全身任何组织，病理改变主要是多脏器纤维化，以肝、胰、脾等实质器官最明显。
Results Congenital syphilis involved many different organs, especially liver, pancreas and spleen. The main pathological change was fibrosis of the organs.
结论血吸虫病肝纤维化如有食道静脉曲张出血倾向者，手术治疗以脾切除附加脾腔端侧分流术为首选。
Conclusion Splenectomy in combination with spleno-caval shunt is a safe and effective operation for the treatment of portal hypertension in patients with schistosomiasis and with bleeding tendency.
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