皮疹的变化从斑丘疹(底部扁平的病变)，一直到小水疱(充满液体的小疱)、脓疱，大约10天左右伴随而来的便是结痂。
Evolution of the rash from maculopapules (lesions with a flat bases) to vesicles (small fluid-filled blisters), pustules, followed by crusts occurs in approximately 10 days.
毛囊性丘疹和脓疱在青春期加重，并伴有畏光、结膜干燥、睑缘炎。
Follicular pustular and papules aggravated in the puberty with photophobia, xeroma and blepharitis.
以炎性结节和囊肿的出现为特征，伴随有粉刺、丘疹和脓疱或颜面部总皮损计数大于125个。
Severe acne is characterized primarily with the presence of inflammatory nodules and cysts. Also present are comedones, papules, and pustules or total lesion count of greater than 125 on the face.
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