遗传性球形红细胞增多症中，窦状隙被RBC塞满，球形红细胞的渗透性脆性增加，因为RBC每单位体积的表面积减少。
The sinusoids are packed with RBC's in this case of hereditary spherocytosis. The osmotic fragility of spherocytes is increased, because the RBC's have decreased surface area per unit volume.
结果表明，老年大鼠变形红细胞增多，膜表面积缩减，膜渗透脆性、膜脂区微粘度升高。
The results showed that the Fercentage of abnormal cells of aged rat is much higher than that of the voung ones. Decrease of surface area of cell membrane and sphere of its shape were observed.
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