新形成的单阳性（single-positive，SP）胸腺细胞在向外周组织迁移之前需要在胸腺髓质（thymic medulla）中经历进一步成熟蜕变的过程。
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T细胞的阴性选择发生在 胸腺髓质 ( thymus medulla )，阴性选择是对自身抗原具有较强免疫应答能力的T细胞克隆通过诱导T细胞的程序性死亡进行清除。不被清除的形成克隆无反应性。
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作者认为，胸腺皮质和髓质都接受副交感的胆碱能神经纤维的支配，后者对胸腺细胞和肥大细胞等可能起调节作用。
This study suggests that the cortex and medulla of thymus are innervated by parasympathetic cholinergic nerve fibers, which may regulate the thymocytes and mast cells.
在各发育期中华鳖胸腺皮质、髓质交界处和髓质区有明显的囊状胸腺小体和交错突细胞。
During development period, there were cystoid thymic corpuscles and interdigitating cells in thymic medulla and cortico-medullary border.
试验组胸腺小叶增多，皮质增厚，淋巴细胞密集，髓质比例减小，胸腺小体减少、减小；
The thymic lobule of experiment group increased, the thymic cortex incrassated and the lymphocyte became coarctate, the portion of thymic medulla decreased and thymic corpuscle enlarged and increased.
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