第三，他们设计让老鼠在它们没有其他皮肤问题的情况下，在它们的皮肤里产生高水平的胸腺基质淋巴细胞生成素。

Thirdly, they engineered mice to produce high levels of TSLP in their skin in the absence of other skin problems.

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在胸腺里，未成熟的T细胞表面有成千上万的分别不同的受体，这些受体由随机基因重新安排产生。

In the thymus, immature t cells display on their surface many thousands of unique receptors, generated by random gene rearrangements.

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他们发现这种敲除基因的小鼠骨髓中的淋巴细胞较正常鼠少50%，产生特异免疫细胞的胸腺较正常鼠少80%。

They found that the knockout mice had 50 percent fewer lymphocytes in their bone marrow and 80 percent fewer in their thymus, a collection of glands that helps produce specialized immune cells.

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