唐氏综合征患者的血清甲胎蛋白升高20 - 25%，胎儿有神经管畸形时甲胎蛋白值也升高。

Maternal serum alpha-fetoprotein is elevated in 20-25% of all cases of Down syndrome, and it is elevated in fetal neural tube deficits.

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甲胎蛋白是癌胚蛋白，其浓度的高低反映了肝脏损害的程度(除胎儿期外)。

AFP is an carcinoma embryo protein, and its concentration (except in embryo phase) indicates the degree of liver injury.

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