【Key words】 BNX mice； biology characteristic； tumor animal model； transgene；
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建立恶性肿瘤动物模型是医学科研工作者重要的研究手段。
Animal model of malignant tumor is a important medical research methods.
目的探讨亚硝基乙基脲（NEU）经胎盘诱发脑肿瘤动物模型的时间和剂量依赖性。
Objective To study time and dose dependence of animal models with brain neoplasms induced transplacentally with N-ethyl-N-nitrosourea (NEU).
肿瘤动物模型是研究肿瘤免疫学、临床前期评价肿瘤治疗方案有效性和安全性的重要前提。
Tumor model of animals is significant for the studies on tumor immunology and preclinical evaluation on the effectiveness and safety of some tumor therapy strategies.
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