DC数量减少和功能缺陷,也是肿瘤细胞逃避机体免疫监视的机制之一。
The decreased infiltration and functional deficiency of DCs may also contribute to tumor cells evading from surveillance of immune system.
一些肿瘤细胞譬如T细胞淋巴瘤el 4细胞等也表达CD 47分子,抑制机体吞噬细胞功能逃逸免疫系统的免疫监视。
Some tumor cells (e. g., t lymphoma EL4 cells) express CD47 and block phagocytosis of phagocytes in order to escape from the surveillance of immune system.
NKG2D介导的细胞免疫应答对于肿瘤或感染起着重要的免疫监视作用,同时与某些自身免疫性疾病也密切相关。
The cellular immune response mediated by NKG2D not only play an important role in immunosurveillance against tumor and infection, but also participate in some auto-immune diseases.
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