生物材料表面肝素固定化修饰技术是改善生物材料表面抗凝性能和生物相容性的一种有效方法。

Immobilization of heparin onto the surfaces of biomaterials is an effective approach for improving their anticoagulant properties and biocompatibility.

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许多研究者通过物理或化学的方法将肝素固定到材料表面，一定程度上改善了材料表面的抗凝血活性。

Many researchers have fixed heparin onto the surface of material through physical or chemical means. To some extent the anticoagulant activity of these materials has been improved.

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本文针对生物材料表面肝素固定化修饰技术的原理思想、实验研究和运用等方面做一综述，并展望了肝素固定化技术的前景。

In this article are reviewed the relevant principle, experimental researches and applications. Finally, a prospect for heparin immobilization is made as well.

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