孤独症是一个严重的，终生的且残障的状况，而且如果没有得到正确的支持可能会对个人及家庭产生严重的后果。
Autism is a serious, lifelong and disabling condition and without the right support it can have a profound effect on individuals and families.
1842年他兄弟的死是一次深刻的感情冲击，可能同时也影响了他的决定，使其和父母一起生活而且终生未娶。
The death of his brother in 1842 was a profound emotional shock and may have influenced his decision to live with his parents and never to marry.
1842年他兄弟的死对他打击很大，可能同时也影响了他的决定，使其和父母一起生活而且终生未娶。
The death of his brother in 1842 was a profound emotional shock and may have influenced his decision to live with his parents and never to marry.
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