本课题制备叶酸(FA)偶联羟丙基壳聚糖(HPCS),探索一种有效且靶向的反义寡核苷酸药物载体,使所制备药物能够有效地降低肿瘤细胞中P-gp糖蛋白的表达,从而抑制肿瘤细胞多药耐...
基于106个网页-相关网页
本文利用环氧丙烷对壳聚糖(CTS)进行改性,对反应条件进行控制,制备了具有良好水溶性的羟丙基壳聚糖(HPCTS),探讨了主要的反应条件对产物取代度的影响,对产物进行了结构表征和性能研究,并对其在织物整理上的应用进行了研究。
基于56个网页-相关网页
本文制备叶酸(FA)和胆固醇琥珀酸单酯(CHS)共修饰的羟丙基壳聚糖(HPCHS),作为叶酸靶向pH响应性胶束用于抗癌药物阿霉素(DOX)的输运,考察了胶束的载药性能及pH响应机理,并研究了胶束的细胞毒性及肿瘤靶...
基于40个网页-相关网页
...,利用叶酸分子中的羧基与HCS中的活性基团氨基发生酰胺反应,得到叶酸偶联羟丙基壳聚糖(folate-hydroxypropyl-chitosan,FHCS),以期达到药物缓释和靶向的双重效果。
基于2个网页-相关网页
The results showed that less injury was made to corneal epithelial cells by the hydroxypropyl chitosan/gelatin/chondroitin sulfate blend membrane than the others. This kind of membrane benefited the growth and adhesion of corneal epithelial cells.
实验结果表明羟丙基壳聚糖/明胶/硫酸软骨素共混膜对细胞的损伤最小,有利于细胞在膜上的贴附和生长,表现出良好的细胞相容性,有望作为角膜细胞载体体外构建组织工程化角膜,确定为本研究的角膜内皮载体材料。
参考来源 - 壳聚糖基组织工程化角膜内皮细胞载体的制备与性质研究After wheat seedlings were sprayed with 0.3% hydroxypropyl chitosan aqueous solution,the activities of nitrate reductase,ribulose-1,5-bisphosphate carboxylase,polyphenol oxidase and superoxide dismutase and the chlorophyll content of wheat seedling leaves from five different periods were measured.
利用0.3%羟丙基壳聚糖溶液对小麦幼苗进行喷洒处理,在幼苗发育的5个时段对4种酶活性和叶绿素含量进行测定。
参考来源 - 羟丙基壳聚糖对小麦幼苗生理功能的影响·2,447,543篇论文数据,部分数据来源于NoteExpress
目的:研究不同取代度的羟丙基壳聚糖膜的生物相容性及其取代度对生物降解性的影响。
ObjectiveTo investigate the biocompatibility of hydroxypropylated chitosan film with diverse degrees of substitution and the influences of its degrees of substitution to biodegradability.
结果表明,所制得的羟丙基壳聚糖具有良好的溶解性能,用其整理出的涤纶织物具有较好的抗静电和抗菌性能。
The results showed that HPCTS had good water solubility and the polyester fabrics had good antistatic and antibacterial activity.
应用推荐