美金刚属于兴奋性氨基酸受体拮抗剂,用于治疗中重度至重度阿尔茨海默型痴呆。盐酸美金刚片为白色至类白色、双面凸起的椭圆形薄膜衣片,两面各有一条刻痕。
...改善阿尔茨海默病(AD)症状。目前主要有:单胺氧化酶抑制剂、腺苷受体拮抗剂、NMDA受体拮抗剂。成功的药物如美金刚(memantine)是一种NMDA受体拮抗剂,可以抑制兴奋性氨基酸的神经毒性而不干扰学习、记忆所需的短暂的谷氨酸生理性释放。
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盐酸美金刚 Menantine Hydrochloride ; Memantine ; Namenda ; Mandelic Acid
盐酸美金刚片 Memantine Hydrochloride Tablets ; Memantine Hydrochlo ; MemantineHydro
美金刚胺 Memantine ; dimethyl-1-aminoadamantane
盐酸美金刚胺 Memantine hydrochloride ; Memantine HCl ; Menantine ; Memant
美金刚片 Memantine Hydrochloride Tablet ; Memantine
盐酸美金刚杂质A Memantine Hydrochloride related compound
盐酸美金刚杂质B Memantine Hydrochloride related compound
盐酸美金刚杂质D Memantine Hydrochloride related compound
盐酸美金刚杂质C Memantine Hydrochloride related compound
在这44名患者中,其中50%还接受美金刚辅助治疗。
Of the 44 patients, 50% also received adjunctive therapy with memantine.
13名病人在他们截肢之后(有些病人也在截肢前)服用美金刚胺持续4个星期。
Thirteen patients took memantine for four weeks after their amputations (and sometimes just before, as well).
让他们欣慰的是,他们发现美金刚胺不但减少了大脑的改变,而且也降低了患肢疼痛的次数和强度。
To their delight, they discovered that memantine not only reduced changes in the brain, it also decreased both the incidence and the intensity of phantom pain.
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