美伐他汀本品为白色或类白色结晶性粉末。本品在丙酮中溶解,在乙醇、乙酸乙酯中略溶,在水中不溶。
...美伐他汀(COMPACTIN或Mevastatin),是一种真菌的次生代谢产物,属HMG-CoA还原酶抑制剂,其作用是竞争性抑制HMG-CoA还原酶,该酶是胆固醇生物合成的限...
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As precursors of biosynthesis,fatty acids are sure influences in biosynthesis. Adding of glycerol has no significant effect on the yield of mevastatin but obvious on thalli biomass.
脂肪酸作为合成前体,对美伐他汀的生物合成有明显的影响,甘油的添加没有显著影响美伐他汀的产量,但对菌体生物量有明显的影响。
参考来源 - 基于代谢途径的前体对美伐他汀生物合成的影响Mevastatin is one of the statins, which is usually used as leads of provastatin.
美伐他汀是他汀类药物中的一种,通常作为普伐他汀的前体。
参考来源 - 美伐他汀提取工艺研究·2,447,543篇论文数据,部分数据来源于NoteExpress
美伐他汀于1976年首次报道,是一种由若干种青霉菌属和红曲菌属真菌产生的双萜。
Mevastatin is a diterpene produced by several species of the genera Penicillium and Monascus first reported in 1976.
美伐他汀是3羟甲基戊二酰辅酶a还原酶的有效的竞争性抑制剂,它是一种胆固醇生物合成调解酶。
Mevastatin is a potent competitive inhibitor of 3-hydroxy-3-methyl-glutaryl-coa reductase, a regulatory enzyme for cholesterol biosynthesis.
美伐他汀是3羟甲基戊二酰辅酶a还原酶的有效的竞争性抑制剂,它是一种胆固醇生物合成调解酶。
Mevastatin is a potent competitive inhibitor of 3-hydroxy-3-methyl-glutaryl (HMG) -coa reductase, a regulatory enzyme for cholesterol biosynthesis.
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