不幸的是，在1976年7月的一场特大洪水中，这条游人如织的道路上发生了科罗拉多州历史上最惨痛的自然灾害。

Tragically, the heavily traveled tourist route became the site of the worst natural disaster in Colorado's history during a catastrophic flash flood in July 1976.

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在该药上市后期间，已报道发生其他包括以硬结、蜂窝织炎、血肿、脓肿、无菌脓肿以及坏死为指征的注射部位反应事件。

In the postmarketing period, additional cases of injection site reaction with features including induration, cellulitis, hematoma, abscess, sterile abscess, and necrosis, have been reported.

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责任中心：责任中心即在某一组织内能控制成本的发生或收入的创造的任何地点。

Responsibility center: a responsibility center is any point within an organization where control over the incurrence of cost or the generating of revenues is found.

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