细胞周期(Cell Cycle)是指细胞从一次分裂完成开始到下一次分裂结束所经历的全过程,细胞的遗传物质复制并均等地分配给两个子细胞。
...的时相性激活,它们通过对相应底物磷酸化,趋使着细胞完成细胞周期。这些蛋白激酶的时相性激活,依赖于一类呈细胞周期特异性表达,累积与分解的蛋白质,称之为细胞周期素(cyclins)。cyclins的时相起伏(即细胞周期特异性的cyclins合成与降解)是细胞周期正常运行的基本前提。
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目的分析细胞周期素依赖激酶4 (CDK4)在颌骨软骨肉瘤的表达及意义。
AIM To analyze the expression and significance of cyclin dependent kinase 4 (CDK4) in chondrosarcoma of the jaws.
结论:细胞周期素d1的扩增和P 16的缺失与肺癌细胞的高增殖活性密切相关。
CONCLUSION: the high amplification of Cyclin D1 and the high deletion of P16 gene is closely related to the high activity of proliferation of lung cancer.
结果发现,主动脉平滑肌细胞可表达细胞周期素d,其免疫反应产物主要位于细胞核内。
Results Rabbit smooth muscle cells could express cyclin d, the reactant of immune reaction was mainly located in nuclei.
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