组蛋白乙酰化酶(histone acetyltransferases,HATs)是催化组蛋白引起乙酰化修饰的酶,决定心肌组织中组蛋白乙酰化修饰水平,从而影响心脏发育基因的时序表达调...
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...:基因表达的精确控制是细胞增殖分化和器官正常生长和发育的基础,基因转录和激活程序依赖于组蛋白乙酰化酶(histone acetylase,HAT)和组蛋白去乙酰化酶(histone deacetylase,HDAC)的协同作用。
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由组蛋白乙酰化酶 histone acetylase ; HAT
主要由组蛋白乙酰化酶 histone acetylase ; HAT
组蛋白去乙酰化酶 HDAC ; histone deacetylase ; histone deacetylases HDACs ; hi stone deacetyltransferases
即组蛋白乙酰化酶 histoneacetylase
组织蛋白去乙酰化酶 HD
人组织蛋白去乙酰化酶 Human HD ; Human Histone Deacetylase ELISA KitELISA ; HD ELISA Kit
组蛋白脱乙酰化酶 histone deacetylase
和组蛋白去乙酰化酶 Histone Deacetyltranferase ; histone deacetylase
探讨组蛋白脱乙酰化酶 histone deacetylase ; HDAC
组蛋白乙酰化和去乙酰化由一对功能相互拮抗的蛋白酶——组蛋白乙酰基转移酶和组蛋白去乙酰化酶负责。
The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other, which are histone transacetylase and histone deacetylase.
他们发现,大脑中有一个“开关”控制瘦素的作用,它就是一种名为组蛋白去乙酰化酶5(HDAC5)的酶。
They have discovered an enzyme - histone deacetylase 5 (HDAC5) - has a significant influence on the effect of the hormone.
组蛋白去乙酰酶抑制剂可提高组蛋白的乙酰化水平,并对一些非组蛋白成分产生影响,从而调节某些特定基因的表达。
Histone deacetylase inhibitors increase the acetylation level of histone as well as some non-histone proteins, and specifically modulate some gene expression.
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