血液凝固过程中形成的纤维蛋白被分解液化的过程,叫纤维蛋白溶解[现象] fibrinolysis(简称纤溶)。纤溶活性异常增强,即纤溶亢进。纤溶亢进又分为原发性纤溶亢进和继发性纤溶亢进,可致出血。血纤维蛋白溶酶作用于纤维蛋白原或纤维蛋白,能将其多肽链的赖氨酸结合部位切断使之溶解的现象。由此产生的分解产物为FDP。纤溶过程也称血液凝固的第四相。 纤溶的激活物(纤溶酶原和纤维蛋白溶解酶即纤溶酶)和抑制物以及纤溶的一系列酶促反应,总称为纤溶系统。
结论:妇宝胶囊的止血机制主要通过促进内源性和外源性凝血系统,抑制纤维蛋白溶解系统达到目的。
Conclusion: the main hemostatic mechanism of Fubao capsule was to stimulate the intrinsic and extrinsic blood coagulation system and to inhibit fibrinolysis system.
简介人体纤维蛋白溶解系统的生理学背景,对以此为依据建立的纳豆激酶溶栓活性测定方法进行了概括总结。
The physiological background of the human fibrinolytic system is briefly introduced, and, on the basis of that, assay methods for the thrombolysis activity of nattokinase are set up.
纤溶酶原激活物抑制物1 (PAI - 1)是血浆纤维蛋白溶解系统的重要组成物之一,对维持血浆纤溶系统的稳定起重要作用。
Plasminogen activator inhibitor-1 (PAI-1) is one of the important components of the plasma fibrinolytic system and plays an key role in maintaining its stability.
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