目的：探讨难治性少见病例——系统性红斑狼疮继发雷诺综合征，指端溃疡疼痛的治疗方法。

Object: to Investigate the treatment of Raynaud's syndrome (RS) succeeded Systemic lupus erythematosus (SLE) with finger tip ulcer and pain.

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已有研究表明瘦素与多种皮肤疾病相关，如白塞综合征、系统性红斑狼疮、硬皮病、天疱疮等。

Recent studies have found that many kinds of dematosis diseases are concerned with the change and different content of leptin and its receptors.

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