「红豆杉〈Taxus cuspidata Sieb.et.Zucc.〉,别名紫杉。叶和茎有毒。马、骡、牛、猪和羊等家畜在冬季喜食其叶而发生中毒。急性中毒初期有兴奋、呕吐和流涎,而后出现呼吸困难、心跳缓慢、体温下降、皮肤及四肢厥冷、知觉麻木、便秘、腹部鼓胀、血尿和尿闭等,中毒后期呈现运动失调以致痉挛和昏迷,可因心跳停止而突然死亡。
结果表明紫杉醇、三尖杉酯碱、高三尖杉酯碱及喜树碱对B16BL6和HT1080细胞增殖均有很强的抑制作用。
Results demonstrated that taxol, harringtonine, homoharringtonine and camptothecin exhibited significant inhibition of cell growth of B16BL6 and HT1080 cells.
他们发现这种协同作用也发生在脂质体和长春新碱或紫杉醇。
They also found that this synergy occurred with trastuzumab and either paclitaxel or vincristine.
在第二项试验中,来自旧金山Genentech公司的Ingrid Wertz博士和他的同事研究的是包括紫杉醇和长春新碱在内的一大类处方类抗癌药物。
In the second study, Dr. Ingrid Wertz of Genentech in San Francisco and her colleagues focused on certain widely prescribed anti-cancer drugs, including Taxol and vincristine.
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